Insomnia selector
Choose the guideline lens (AASM / ESRS / ACP), the insomnia pattern, age and comorbidities — get the plan: CBT-I first-line for everyone, then (if a drug is added) a pattern-matched, Beers-aware choice — DORAs / low-dose doxepin for maintenance, short-acting agents for onset — with the drugs to avoid flagged.
Guideline lens
Insomnia patternchoose one
Chronicitychoose one
Age groupchoose one
Comorbidities
CBT-I statuschoose one
First-line (all guidelines)
CBT-I — for every patient with chronic insomnia, before or instead of medication
If a drug is added
sleep-maintenance → DORA / low-dose doxepin — adjunct, time-limited, shared decision
Notes
- • CBT-I is first-line for ALL chronic insomnia (ACP, AASM, ESRS) — offer it before or instead of medication; digital/guided-digital CBT-I is an accepted alternative when in-person access is limited. Medication is an adjunct, generally time-limited.
- • CBT-I not yet tried: prioritize it. If a drug is used while CBT-I is arranged, keep it short-term and pattern-matched (onset vs maintenance).
- • AASM rates each drug individually (all weak-strength) and, in 2026, suggests CBT-I alone over routinely starting CBT-I + drug together. Trazodone and OTC antihistamines are recommended against.
Suggested drug classesPer AASM 2026.
Select the insomnia pattern to begin.
Switch the lens to see the DORA/melatonin difference: ESRS ranks DORAs strongest; AASM rates each drug (all weak) and is against trazodone/antihistamines.
Guidelines
- 2026AASM — AASM guidelines — behavioral (2021) + pharmacologic (2017) + combination (2026). CBT-I first-line; per-drug GRADE (all weak). link
- 2023ESRS — European Insomnia Guideline update (J Sleep Res 2023). CBT-I very strong; DORAs strongest pharmacologic (daridorexant); PR-melatonin ≥55 only. link
- 2016ACP — ACP — Management of Chronic Insomnia (2016; CBT-I first, drugs only after CBT-I; source of the CBT-I-first framing). link
References
- [1]AASM — Pharmacologic Treatment of Chronic Insomnia (JCSM 2017) + Behavioral and Psychological Treatments (2021) + Combination Treatment (2026). CBT-I first-line; per-drug GRADE (all weak); trazodone/antihistamines against. Beers Criteria 2023 (avoid benzodiazepines/Z-drugs/anticholinergics in older adults). link
- [2]Riemann D, et al. European Insomnia Guideline update. J Sleep Res 2023;32:e14035. CBT-I very strong; DORAs (daridorexant) strongest pharmacologic; prolonged-release melatonin age ≥55. link
- [3]Qaseem A, et al. Management of Chronic Insomnia Disorder in Adults: ACP Clinical Practice Guideline. Ann Intern Med 2016;165:125 (CBT-I first). Canadian: PEER simplified guideline, CFP 2024; Choosing Wisely Canada (deprescribe sedative-hypnotics). link